Hypertonic solution-induced preconditioning reduces inflammation and mortality rate
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چکیده
منابع مشابه
Hypertonic saline reduces inflammation and enhances the resolution of oleic acid induced acute lung injury
BACKGROUND Hypertonic saline (HTS) reduces the severity of lung injury in ischemia-reperfusion, endotoxin-induced and ventilation-induced lung injury. However, the potential for HTS to modulate the resolution of lung injury is not known. We investigated the potential for hypertonic saline to modulate the evolution and resolution of oleic acid induced lung injury. METHODS Adult male Sprague Da...
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OBJECTIVE Volume replacement in septic patients improves hemodynamic stability. This effect can reduce the inflammatory response. The objective of this study was to evaluate the effect of 7.5% hypertonic saline solution versus 0.9% normal saline solution for volume replacement during an inflammatory response in endotoxemic rats. METHODS We measured cytokines (serum and gut), nitrite, and lipi...
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Hypertonic saline has been shown to modulate cell shape and the response of components of the innate immune response. However, the effect of hypertonic saline on the macrophage remains unknown. We hypothesized that hypertonic preconditioning would impair subsequent inflammatory mediator signaling through a reduction in stress fiber polymerization and mitogen-activated protein kinase activity af...
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Although safe doses of radiation have been determined, concerns about the harmful effects of low-dose radiation persist. In particular, to date, few studies have investigated the correlation between low-dose radiation and disease development. Asthma is a common chronic inflammatory airway disease that is recognized as a major public health problem. In this study, we evaluated the effects of low...
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ژورنال
عنوان ژورنال: Journal of Inflammation
سال: 2019
ISSN: 1476-9255
DOI: 10.1186/s12950-019-0220-4